Mean Corpuscular Hemoglobin (MCH)

What is a Mean Corpuscular Hemoglobin (MCH)? Why is the test done? Everything around this, that you should know, in this post, and of course our doctors are always there to help you. Just fill in your details in the form below and we will answer all your questions for FREE!

What is the Mean Corpuscular Hemoglobin (MCH) test?

MCH measures the average amount of haemoglobin in each red blood cell (RBC). Haemoglobin is a protein present in red blood cells (RBCs) which carries the oxygen from the lung to the tissues of the body.

Also Read: Folate Test
Why is the Mean Corpuscular Hemoglobin (MCH) test done?

This test helps in evaluating the proper distribution of oxygen among all the body organs.

Its value is related to two other values i.e., Mean Corpuscular Volume (MCV) and Mean Corpuscular Hemoglobin Concentration (MCHC). These three together are called RBC indices.

What is the normal value of Mean Corpuscular Hemoglobin (MCH)?

The units of measurement of MCH are picograms (pg).

The normal range is 27- 33 pg per cell

What does a low Mean Corpuscular Hemoglobin (MCH) value indicate?

The MCH value below 27 pg is considered low. It usually indicates iron deficiency anaemia and the symptoms can be:

  • Headache
  • Weakness
  • Pale skin
  • Yellow conjunctiva
  • Nails breakage
  • Shortness of breath
  • Chest pain
  • Fast heartbeat
  • Lightheadedness
What causes low Mean Corpuscular Hemoglobin (MCH)?

Iron deficiency anaemia is the main cause of low MCH. It may be due to:

  • Low iron consumption
  • Trauma or injury
  • Blood loss

In some rare cases, it may be caused by thalassemia which is a genetic disorder and causes improper production of hemoglobin.

What does a high Mean Corpuscular Hemoglobin (MCH) value indicate?

The MCH value above 33 pg is considered high. It usually indicates macrocytic anaemia due to a deficiency of Vitamin B12 and folate. These two vitamins are required to make enough RBCs.

Due to their deficiency, the blood cells become larger in size and carry much haemoglobin per cell. So, the symptoms will be presented in the same way as with a low MCH value.

What causes high Mean Corpuscular Hemoglobin (MCH)?

Macrocytic anemia is the main cause of high MCH value which is the result of low vitamin B12 or folate. However, low MCH can also be due to:

  • Liver disease
  • An infection
  • Excessive alcohol consumption
  • Overactive thyroid
  • Complications of any cancerous condition
  • Taking prolonged medication containing estrogen

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