Lichen amyloidosis is a cutaneous condition characterized by the appearance of occasionally itchy lichenoid papules, appearing on the shins bilaterally.
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The disease occurs most frequently in persons aged 50-60 years. It is more common in males than in females.
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It is believed to be more common in persons of Chinese ancestry
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Amyloid deposits in lichen amyloidosis bind to antikeratin antibodies.These deposits contain sulfhydryl groups, pointing to altered keratin as a source for these deposits.
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Presents as intensely pruritic, red brown hyperkeratotic papules most commonly seen in pretibial surfaces i.e on shins.
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A skin biopsy may be performed in lichen amyloidosis.
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• Sedative antihistamines
• Topical and intralesional steroids
• Topical dimethyl sulfaoxide , a chemical solvent
• Surgical care :Include laser vaporization, dermabrasion and excision of individual lesion.Any of these can be the choice of treatment.
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• Prurigo nodularis
• Lichen sclerosus et Atrophicus
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